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http://dspace.centre-univ-mila.dz/jspui/handle/123456789/3878| Title: | Etude phytochimique et l’activité antimicrobienne de deux plantes médicinales |
| Authors: | Nawal, Namous,Bougaada , Maroua |
| Keywords: | Urtica dioica L, Saussurea costus, activité antioxydante, radical DPPH, activité antibactérienne, activité anti-inflammatoire. Urtica dioica L, Saussurea costus, antioxidant activity, radical DPPH, antibacterial activity, anti-inflammatory activity. |
| Issue Date: | Jun-2024 |
| Publisher: | university centre of abdelhafid boussouf -mila- |
| Citation: | Spécialité : Biochimie Appliquée |
| Description: | Nettle (Urtica dioïque) and Indian costus (Saussurea costus) are two medicinal plants traditionally used to treat a variety of diseases thanks to their antimicrobial properties. Recent studies have explored the phytochemical and antimicrobial properties of these plants to validate their traditional use and identify potential new therapeutic components. In our work, we carried out phytochemical analyses, tests. Microbiological, antioxidant and anti-inflammatory on the three extracts of each plant: methanoic, ethanoic and aqueous in order to determine the bioactive components. The chemical detection on the extracts of the two plants revealed a strong presence of flavonoids, with the highest rate recorded is that of methanoic extract: 107.29 μg QE/ml for nettle and 30.69 μg QE/ml for Indian costus. For antioxidant activity, the Indian costus plant shows that: - Highest DPPH activity is recorded for ethanoic extract with an IC50 of 392.60μg/ml. - The highest activity of FRAP and Phenanthhroline is recorded for methanoic extract (A0.5 = 46.68 μg/ml and A0.5 = 53.45 μg/ml respectively). While for nettle, the highest antioxidant activity of ABTS is recorded for ethanoic extract with an IC50 of 178.67μg/ml. The anti-inflammatory efficacy of the three extracts of the two plants was also evaluated. The aqueous nettle extract has a high activity: A0.5 = 299.41 μg/ml. Antibacterial activity was performed on four bacterial strains. The results obtained indicate that the two methanoic and ethanoic extracts of Indian costus saw a powerful antibacterial activity against the strains of Staphylococcus aureus and Bacillus subtilis. The methanoic extract of Urtica dioica shows a powerful antibacterial activity against Staphylococcus aureus strains. |
| URI: | http://dspace.centre-univ-mila.dz/jspui/handle/123456789/3878 |
| Appears in Collections: | Natural and life sciences |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| Etude phytochimique et l’activité antimicrobienne de deux plantes médicinales.pdf | 4,36 MB | Adobe PDF | View/Open |
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